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The Antidepressant-Like and Analgesic Effects of Kratom Alkaloids are accompanied by Changes in Low Frequency Oscillations but not ΔFosB Accumulation

The Antidepressant-Like and Analgesic Effects of Kratom Alkaloids are accompanied by Changes in Low Frequency Oscillations but not ΔFosB Accumulation

The following information is pulled from a study. The study details and link to the source are at the bottom of this post. Mitragyna speciosa (“kratom”), employed as a traditional medicine to improve mood and relieve pain, has shown increased use in Europe and North America. Here, the dose-dependent effects of a purified alkaloid kratom extract...

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Kratom: What science is discovering about the risks and benefits of a controversial herb

Kratom: What science is discovering about the risks and benefits of a controversial herb

Kratom, a traditional Southeast Asian herbal medicine from the leaves of the tropical tree Mitragyna speciosa, has gained favor in the U.S. as a legal high over the past decade. Almost two metric tons of kratom are imported from Southeast Asia monthly. A typical dose of kratom consists of three to five grams, suggesting over 15 million users in...

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Kratom: Fear-worthy Foliage or Beneficial Botanical?

Kratom: Fear-worthy Foliage or Beneficial Botanical?

Depending on what you read, kratom is a dangerous, addictive drug with no medical utility and severe side effects, including overdose and death, or it is an accessible pathway out of undertreated chronic pain and opiate withdrawal. How can the US Drug Enforcement Agency (DEA), medical professionals, and millions of regular kratom users have such divergent views of the...

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Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions

Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions

The following information is pulled from a study. The study details and link to the source are at the bottom of this post. Abstract. The safety and efficacy of kratom (Mitragyna speciosa) for treatment of pain is highly controversial. Kratom produces more than 40 structurally related alkaloids, but most studies have focused on just two of...

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Natural Herb Kratom May Have Therapeutic Effects And Relatively Low Potential For Abuse Or Harm, According To A User Survey

Natural Herb Kratom May Have Therapeutic Effects And Relatively Low Potential For Abuse Or Harm, According To A User Survey

Researchers say findings underscore need for research and regulation, but not an outright ban on sales Using results of a survey of more than 2,700 self-reported users of the herbal supplement kratom, sold online and in smoke shops around the U.S., Johns Hopkins Medicine researchers conclude that the psychoactive compound somewhat similar to opioids likely...

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Current Perspectives on the Impact of Kratom Use

Current Perspectives on the Impact of Kratom Use

The following information is pulled from a study. The study details and link to the source are at the bottom of this post. Abstract The leaves from the tree Mitragyna speciosa, commonly known as Kratom, in the coffee plant family (Rubiaceae) are commonly used in their native habitat of Southeast Asia as a stimulant to sustain...

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